Clinical Outcomes in Statin Treatment Trials
نویسندگان
چکیده
منابع مشابه
Clinical outcomes in statin treatment trials: a meta-analysis.
OBJECTIVE To determine the risk of cardiovascular events and death in patients receiving statin treatment for cholesterol regulation. METHODS Systematic review and meta-analysis of all randomized controlled trials that were published as of April 15, 1997. Primary or secondary prevention trials or regression trials were eligible. MAIN OUTCOME MEASURES All-cause mortality, fatal myocardial in...
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Background: Statins may be protective against viral infection and have been suggested for the treatment of coronavirus disease 2019 (COVID-19). Objective: In this study, we aimed to evaluate the effect of atorvastatin on COVID-19 patients. Methods: Our study is a randomized double-blind controlled clinical trial that constitutes a population of COVID-19 patients admitted to Bu-Ali Sina Hospi...
متن کاملAssociation between treatment toxicity and outcomes in oncology clinical trials.
BACKGROUND Whether or not toxicity predicts clinical outcomes has long been a question regarding cancer treatments. While prior studies have focused on specific cancers, therapies, and toxicities, no comprehensive evidence exists on whether treatment toxicity predicts favorable outcomes. METHODS We abstracted treatment toxicity and clinical outcome data from a sample of phase III oncology ran...
متن کاملStatin Treatment and Clinical Outcomes of Heart Failure Among Africans: An Inverse Probability Treatment Weighted Analysis
BACKGROUND Randomized control trials of statins have not demonstrated significant benefits in outcomes of heart failure (HF). However, randomized control trials may not always be generalizable. The aim was to determine whether statin and statin type-lipophilic or -hydrophilic improve long-term outcomes in Africans with HF. METHODS AND RESULTS This was a retrospective longitudinal study of HF ...
متن کاملStatin myopathy: a common dilemma not reflected in clinical trials.
Although statins are remarkably effective, they are still underprescribed because of concerns about muscle toxicity. We review the aspects of statin myopathy that are important to the primary care physician and provide a guide for evaluating patients on statins who present with muscle complaints. We outline the differential diagnosis, the risks and benefits of statin therapy in patients with po...
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ژورنال
عنوان ژورنال: Archives of Internal Medicine
سال: 1999
ISSN: 0003-9926
DOI: 10.1001/archinte.159.15.1793